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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
TAGL_HUMAN
USC-OGP 2-DE database
:
TAGL_HUMAN
TAGL_HUMAN
General information about the entry
View entry in simple text format
Entry name
TAGL_HUMAN
Primary accession number
Q01995
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Transgelin; AltName: Full=22 kDa actin-binding protein; AltName: Full=Protein WS3-10; AltName: Full=Smooth muscle protein 22-alpha; Short=SM22-alpha;.
Gene name
Name=TAGLN
Synonyms=SM22, WS3-10
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1309
:
pI=8.56; Mw=22246
SPOT OGP-1323
:
pI=6.28; Mw=18705
Cross-references
UniProtKB/Swiss-Prot
Q01995; TAGL_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
TAGL_HUMAN
Primary accession number
Q01995
Secondary accession number(s)
O15542
Sequence was last modified on
January 23, 2007 (version 4)
Annotations were last modified on
March 15, 2017 (version 166)
Name and origin of the protein
Description
RecName: Full=Transgelin; AltName: Full=22 kDa actin-binding protein; AltName: Full=Protein WS3-10; AltName: Full=Smooth muscle protein 22-alpha; Short=SM22-alpha;
Gene name
Name=TAGLN
Synonyms=SM22, WS3-10
Encoded on
Name=TAGLN; Synonyms=SM22, WS3-10
Keywords
Acetylation
;
Actin-binding
;
Complete proteome
;
Cytoplasm
;
Methylation
;
Muscle protein
;
Phosphoprotein
;
Polymorphism
;
Reference proteome
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
M95787; AAA58351.1
; -; mRNA
EMBL
M83106; AAA58375.1
; -; mRNA
EMBL
AF013711; AAC21582.1
; -; Genomic_DNA
EMBL
D17409; BAA21811.1
; -; mRNA
EMBL
D84342; BAA21839.1
; -; Genomic_DNA
EMBL
BC004927; AAH04927.1
; -; mRNA
EMBL
BC065829; AAH65829.1
; -; mRNA
CCDS
CCDS8381.1; -
; .
PIR
JC5577; JS0774
; .
RefSeq
NP_001001522.1; NM_001001522.1
; .
RefSeq
NP_003177.2; NM_003186.3
; .
UniGene
Hs.410977; -
; .
ProteinModelPortal
Q01995; -
; .
SMR
Q01995; -
; .
BioGrid
112739; 50
; .
IntAct
Q01995; 6
; .
MINT
MINT-2805284; -
; .
STRING
9606.ENSP00000278968; -
; .
iPTMnet
Q01995; -
; .
PhosphoSitePlus
Q01995; -
; .
SwissPalm
Q01995; -
; .
BioMuta
TAGLN; -
; .
DMDM
3123283; -
; .
REPRODUCTION-2DPAGE
IPI00216138; -
; .
UCD-2DPAGE
Q01995; -
; .
EPD
Q01995; -
; .
PaxDb
Q01995; -
; .
PeptideAtlas
Q01995; -
; .
PRIDE
Q01995; -
; .
DNASU
6876; -
; .
Ensembl
ENST00000278968; ENSP00000278968
; ENSG00000149591; .
Ensembl
ENST00000392951; ENSP00000376678
; ENSG00000149591; .
Ensembl
ENST00000525531; ENSP00000432054
; ENSG00000149591; .
Ensembl
ENST00000530649; ENSP00000431941
; ENSG00000149591; .
Ensembl
ENST00000532870; ENSP00000432282
; ENSG00000149591; .
GeneID
6876; -
; .
KEGG
hsa:6876; -
; .
CTD
6876; -
; .
DisGeNET
6876; -
; .
GeneCards
TAGLN; -
; .
HGNC
HGNC:11553; TAGLN
; .
HPA
CAB001447; -
; .
HPA
HPA019467; -
; .
MIM
600818; gene
; .
neXtProt
NX_Q01995; -
; .
OpenTargets
ENSG00000149591; -
; .
PharmGKB
PA36324; -
; .
eggNOG
KOG2046; Eukaryota
; .
eggNOG
COG5199; LUCA
; .
GeneTree
ENSGT00550000074447; -
; .
HOGENOM
HOG000232113; -
; .
HOVERGEN
HBG005186; -
; .
InParanoid
Q01995; -
; .
KO
K20526; -
; .
OMA
VEWIVVQ; -
; .
OrthoDB
EOG091G0LY2; -
; .
PhylomeDB
Q01995; -
; .
TreeFam
TF313921; -
; .
SIGNOR
Q01995; -
; .
ChiTaRS
TAGLN; human
; .
GeneWiki
TAGLN; -
; .
GenomeRNAi
6876; -
; .
PRO
PR:Q01995; -
; .
Proteomes
UP000005640; Chromosome 11
; .
Bgee
ENSG00000149591; -
; .
CleanEx
HS_TAGLN; -
; .
ExpressionAtlas
Q01995; baseline and differential
; .
Genevisible
Q01995; HS
; .
GO
GO:0005737; C:cytoplasm
; IEA:UniProtKB-SubCell; .
GO
GO:0030855; P:epithelial cell differentiation
; IDA:UniProtKB; .
GO
GO:0007517; P:muscle organ development
; TAS:ProtInc; .
CDD
cd00014; CH
; 1; .
Gene3D
1.10.418.10; -
; 1; .
InterPro
IPR000557; Calponin_repeat
; .
InterPro
IPR001715; CH-domain
; .
InterPro
IPR003096; SM22_calponin
; .
InterPro
IPR029976; TAGLN
; .
PANTHER
PTHR18959:SF65; PTHR18959:SF65
; 1; .
Pfam
PF00402; Calponin
; 1; .
Pfam
PF00307; CH
; 1; .
PRINTS
PR00888; SM22CALPONIN
; .
SMART
SM00033; CH
; 1; .
SUPFAM
SSF47576; SSF47576
; 1; .
PROSITE
PS01052; CALPONIN_1
; 1; .
PROSITE
PS51122; CALPONIN_2
; 1; .
PROSITE
PS50021; CH
; 1; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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